In order to pick up flagging ratings, the Excel Saga writers introduce a new character: the android lady Ropponmatsu, creation of Dr. Shioji, a brilliant scientist with a mostly-innocent (thank goodness) fixation with small girls. Iwata, of course, becomes hopelessly enamored with Ropponmatsu, completely clueless to the fact that she’s not a living, breathing human. Meanwhile, Excel and Hyatt manage to bungle a seemingly simple mission to deliver a package with a bomb in it, one discovered and disarmed by Ropponmatsu… well, not quite, much to Iwata’s horror.
Hyperactive Excel does anything and everything to try to please her lord, Il Palazzo, who wants to take over the planet. Excel’s misadventures takes her and her partner, the ever-dying Hyatt, all over the world, meeting several strange people as they go. Everything is bizarre and goofy, as any kind of anime or entertainment genre gets mocked and spoofed.
